Protein L-Myc (MYCL)

About Protein L-Myc

Protein L-Myc (MYCL) is a protein from Homo sapiens identified by UniProt accession P12524, 364 residues long. MolForge cross-references it against 0 known binders and 238 disease associations.

Target properties

Protein name	Protein L-Myc
UniProt accession	P12524
Gene	MYCL
Organism	Homo sapiens
Length	364 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (238)

Diseases linked to this target (Open Targets).

neurodegenerative disease · score 0.53
nodular melanoma · score 0.37
desmoplastic melanoma · score 0.37
superficial spreading melanoma · score 0.37
skin squamous cell carcinoma · score 0.37
Endometrial Endometrioid Adenocarcinoma · score 0.37
gastrointestinal stromal tumor · score 0.37
platelet count · score 0.31
hemoglobin measurement · score 0.31
lysophosphatidylcholine measurement · score 0.30

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-P12524-F1	alphafold	PREDICTED	63.75	—

Amino-acid sequence (364 residues)

MDYDSYQHYF YDYDCGEDFY RSTAPSEDIW KKFELVPSPP TSPPWGLGPG AGDPAPGIGP PEPWPGGCTG DEAESRGHSK GWGRNYASII RRDCMWSGFS ARERLERAVS DRLAPGAPRG NPPKASAAPD CTPSLEAGNP APAAPCPLGE PKTQACSGSE SPSDSENEEI DVVTVEKRQS LGIRKPVTIT VRADPLDPCM KHFHISIHQQ QHNYAARFPP ESCSQEEASE RGPQEEVLER DAAGEKEDEE DEEIVSPPPV ESEAAQSCHP KPVSSDTEDV TKRKNHNFLE RKRRNDLRSR FLALRDQVPT LASCSKAPKV VILSKALEYL QALVGAEKRM ATEKRQLRCR QQQLQKRIAY LTGY

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards