About Myosin light chain 4
Myosin light chain 4 (MYL4) is a protein
from Homo sapiens identified by UniProt accession
P12829, 197 residues long.
MolForge cross-references it against 0 known binders and
124 disease associations.
Target properties
| Protein name | Myosin light chain 4 |
|---|
| UniProt accession | P12829 |
|---|
| Gene | MYL4 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 197 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (124)
Diseases linked to this target (Open Targets).
- familial atrial fibrillation · score 0.63
- hypertrophic cardiomyopathy · score 0.54
- heart failure · score 0.39
- cardiovascular disease · score 0.37
- serum non-albumin protein measurement · score 0.30
- Reduced left ventricular ejection fraction · score 0.28
- hypertension · score 0.23
- body fat percentage · score 0.23
- breast adenocarcinoma · score 0.23
- total blood protein measurement · score 0.20
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-P12829-F1 | alphafold | PREDICTED | 90.28 | — |
Amino-acid sequence (197 residues)
MAPKKPEPKK EAAKPAPAPA PAPAPAPAPA PEAPKEPAFD PKSVKIDFTA DQIEEFKEAF SLFDRTPTGE MKITYGQCGD VLRALGQNPT NAEVLRVLGK PKPEEMNVKM LDFETFLPIL QHISRNKEQG TYEDFVEGLR VFDKESNGTV MGAELRHVLA TLGEKMTEAE VEQLLAGQED ANGCINYEAF VKHIMSG
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