Promotilin (MLN)

About Promotilin

Promotilin (MLN) is a protein from Homo sapiens identified by UniProt accession P12872, 115 residues long. MolForge cross-references it against 0 known binders and 171 disease associations.

Target properties

Protein name	Promotilin
UniProt accession	P12872
Gene	MLN
Organism	Homo sapiens
Length	115 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (171)

Diseases linked to this target (Open Targets).

type 1 diabetes mellitus · score 0.32
body fat percentage · score 0.29
blood protein measurement · score 0.27
glioblastoma multiforme · score 0.26
irritability measurement · score 0.26
birth weight · score 0.24
body mass index · score 0.23
lifestyle measurement · score 0.22
grip strength measurement · score 0.22
monocyte count · score 0.22

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-P12872-F1	alphafold	PREDICTED	68.90	—

Amino-acid sequence (115 residues)

MVSRKAVAAL LVVHVAAMLA SQTEAFVPIF TYGELQRMQE KERNKGQKKS LSVWQRSGEE GPVDPAEPIR EEENEMIKLT APLEIGMRMN SRQLEKYPAT LEGLLSEMLP QHAAK

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards