About Interleukin-7
Interleukin-7 (IL7) is a protein
from Homo sapiens identified by UniProt accession
P13232, 177 residues long.
MolForge cross-references it against 0 known binders and
768 disease associations.
Target properties
| Protein name | Interleukin-7 |
|---|
| UniProt accession | P13232 |
|---|
| Gene | IL7 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 177 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (768)
Diseases linked to this target (Open Targets).
- lymphocyte count · score 0.47
- epidermodysplasia verruciformis · score 0.42
- eosinophil count · score 0.40
- leukocyte count · score 0.30
- platelet-to-lymphocyte ratio · score 0.29
- lymphocyte percentage of leukocytes · score 0.28
- neutrophil percentage of leukocytes · score 0.28
- interleukin 7 measurement · score 0.27
- blood protein measurement · score 0.27
- lymphocyte:monocyte ratio · score 0.20
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-P13232-F1 | alphafold | PREDICTED | 73.90 | — |
Amino-acid sequence (177 residues)
MFHVSFRYIF GLPPLILVLL PVASSDCDIE GKDGKQYESV LMVSIDQLLD SMKEIGSNCL NNEFNFFKRH ICDANKEGMF LFRAARKLRQ FLKMNSTGDF DLHLLKVSEG TTILLNCTGQ VKGRKPAALG EAQPTKSLEE NKSLKEQKKL NDLCFLKRLL QEIKTCWNKI LMGTKEH
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