C-C motif chemokine 4 (CCL4)

About C-C motif chemokine 4

C-C motif chemokine 4 (CCL4) is a protein from Homo sapiens identified by UniProt accession P13236, 92 residues long. MolForge cross-references it against 0 known binders and 673 disease associations.

Target properties

Protein name	C-C motif chemokine 4
UniProt accession	P13236
Gene	CCL4
Organism	Homo sapiens
Length	92 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (673)

Diseases linked to this target (Open Targets).

blood protein measurement · score 0.23
C-C motif chemokine 3 measurement · score 0.22
visual perception measurement · score 0.15
neoplasm · score 0.11
oral squamous cell carcinoma · score 0.10
diabetes mellitus · score 0.09
myeloid sarcoma · score 0.09
lung adenocarcinoma · score 0.08
Rheumatoid arthritis · score 0.08
bathing suit ichthyosis · score 0.07

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-P13236-F1	alphafold	PREDICTED	87.68	—

Amino-acid sequence (92 residues)

MKLCVTVLSL LMLVAAFCSP ALSAPMGSDP PTACCFSYTA RKLPRNFVVD YYETSSLCSQ PAVVFQTKRS KQVCADPSES WVQEYVYDLE LN

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards