About Myogenic factor 5
Myogenic factor 5 (MYF5) is a protein
from Homo sapiens identified by UniProt accession
P13349, 255 residues long.
MolForge cross-references it against 0 known binders and
254 disease associations.
Target properties
| Protein name | Myogenic factor 5 |
|---|
| UniProt accession | P13349 |
|---|
| Gene | MYF5 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 255 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (254)
Diseases linked to this target (Open Targets).
- ophthalmoplegia, external, with rib and vertebral anomalies · score 0.55
- External ophthalmoplegia · score 0.42
- scoliosis · score 0.42
- endometrial cancer · score 0.23
- medulloblastoma · score 0.16
- neoplasm · score 0.09
- autosomal recessive spondylocostal dysostosis · score 0.08
- posterior fusion of lumbosacral vertebrae-blepharoptosis syndrome · score 0.07
- cervical rib syndrome · score 0.07
- Klippel-Feil syndrome 3, autosomal dominant · score 0.07
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-P13349-F1 | alphafold | PREDICTED | 63.92 | — |
Amino-acid sequence (255 residues)
MDVMDGCQFS PSEYFYDGSC IPSPEGEFGD EFVPRVAAFG AHKAELQGSD EDEHVRAPTG HHQAGHCLMW ACKACKRKST TMDRRKAATM RERRRLKKVN QAFETLKRCT TTNPNQRLPK VEILRNAIRY IESLQELLRE QVENYYSLPG QSCSEPTSPT SNCSDGMPEC NSPVWSRKSS TFDSIYCPDV SNVYATDKNS LSSLDCLSNI VDRITSSEQP GLPLQDLASL SPVASTDSQP ATPGASSSRL IYHVL
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