C-C motif chemokine 5 (CCL5)

About C-C motif chemokine 5

C-C motif chemokine 5 (CCL5) is a protein from Homo sapiens identified by UniProt accession P13501, 91 residues long. MolForge cross-references it against 0 known binders and 1,083 disease associations.

Target properties

Protein name	C-C motif chemokine 5
UniProt accession	P13501
Gene	CCL5
Organism	Homo sapiens
Length	91 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (1083)

Diseases linked to this target (Open Targets).

breast adenocarcinoma · score 0.17
blood protein measurement · score 0.14
neoplasm · score 0.12
breast cancer · score 0.11
hepatocellular carcinoma · score 0.11
cancer · score 0.11
CCL5 measurement · score 0.10
infection · score 0.10
infect · score 0.10
Rheumatoid arthritis · score 0.10

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-P13501-F1	alphafold	PREDICTED	88.46	—

Amino-acid sequence (91 residues)

MKVSAAALAV ILIATALCAP ASASPYSSDT TPCCFAYIAR PLPRAHIKEY FYTSGKCSNP AVVFVTRKNR QVCANPEKKW VREYINSLEM S

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards