About Secretogranin-2
Secretogranin-2 (SCG2) is a protein
from Homo sapiens identified by UniProt accession
P13521, 617 residues long.
MolForge cross-references it against 0 known binders and
173 disease associations.
Target properties
| Protein name | Secretogranin-2 |
|---|
| UniProt accession | P13521 |
|---|
| Gene | SCG2 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 617 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (173)
Diseases linked to this target (Open Targets).
- sodium measurement · score 0.27
- platelet-derived growth factor BB measurement · score 0.25
- interferon gamma measurement · score 0.24
- fibroblast growth factor basic measurement · score 0.24
- vascular endothelial growth factor measurement · score 0.24
- granulocyte colony-stimulating factor measurement · score 0.24
- interleukin 12 measurement · score 0.24
- interleukin 10 measurement · score 0.24
- interleukin-6 measurement · score 0.24
- interleukin 17 measurement · score 0.24
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-P13521-F1 | alphafold | PREDICTED | 57.86 | — |
Amino-acid sequence (617 residues)
MAEAKTHWLG AALSLIPLIF LISGAEAASF QRNQLLQKEP DLRLENVQKF PSPEMIRALE YIENLRQQAH KEESSPDYNP YQGVSVPLQQ KENGDESHLP ERDSLSEEDW MRIILEALRQ AENEPQSAPK ENKPYALNSE KNFPMDMSDD YETQQWPERK LKHMQFPPMY EENSRDNPFK RTNEIVEEQY TPQSLATLES VFQELGKLTG PNNQKRERMD EEQKLYTDDE DDIYKANNIA YEDVVGGEDW NPVEEKIESQ TQEEVRDSKE NIEKNEQIND EMKRSGQLGI QEEDLRKESK DQLSDDVSKV IAYLKRLVNA AGSGRLQNGQ NGERATRLFE KPLDSQSIYQ LIEISRNLQI PPEDLIEMLK TGEKPNGSVE PERELDLPVD LDDISEADLD HPDLFQNRML SKSGYPKTPG RAGTEALPDG LSVEDILNLL GMESAANQKT SYFPNPYNQE KVLPRLPYGA GRSRSNQLPK AAWIPHVENR QMAYENLNDK DQELGEYLAR MLVKYPEIIN SNQVKRVPGQ GSSEDDLQEE EQIEQAIKEH LNQGSSQETD KLAPVSKRFP VGPPKNDDTP NRQYWDEDLL MKVLEYLNQE KAEKGREHIA KRAMENM
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