Metallothionein-1G (MT1G)

Homo sapiens — UniProt P13640

Gene: MT1GHomo sapiensSwissProt reviewed

About Metallothionein-1G

Metallothionein-1G (MT1G) is a protein from Homo sapiens identified by UniProt accession P13640, 62 residues long. MolForge cross-references it against 0 known binders and 125 disease associations.

Target properties

Protein nameMetallothionein-1G
UniProt accessionP13640
GeneMT1G
OrganismHomo sapiens
Length62 residues
Molecular weight—
EC numbers—
Target classUNCLASSIFIED
Subcellular location—
Keywords—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tierMEDIUM
Druggability score—
Pocket score—
Max clinical phase—

Disease associations (125)

Diseases linked to this target (Open Targets).

  • hepatocellular carcinoma · score 0.12
  • neoplasm · score 0.10
  • nonpapillary renal cell carcinoma · score 0.08
  • cancer · score 0.05
  • papillary thyroid carcinoma · score 0.05
  • ulcerative colitis · score 0.04
  • clear cell renal carcinoma · score 0.03
  • gonorrhea · score 0.03
  • lymph node metastatic carcinoma · score 0.02
  • Kidney Oncocytoma · score 0.02

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

StructureSourceMethodMean pLDDTResolution (Å)
AF-P13640-F1alphafoldPREDICTED78.98—

Amino-acid sequence (62 residues)

MDPNCSCAAA GVSCTCASSC KCKECKCTSC KKSCCSCCPV GCAKCAQGCI CKGASEKCSC CA

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Quick facts

UniProtP13640
GeneMT1G
OrganismHomo sapiens
Length62
Binders0
Diseases125
View on UniProt