Tartrate-resistant acid phosphatase type 5 (ACP5)

About Tartrate-resistant acid phosphatase type 5

Tartrate-resistant acid phosphatase type 5 (ACP5) is a protein from Homo sapiens identified by UniProt accession P13686, 325 residues long. MolForge cross-references it against 0 known binders and 547 disease associations.

Target properties

Protein name	Tartrate-resistant acid phosphatase type 5
UniProt accession	P13686
Gene	ACP5
Organism	Homo sapiens
Length	325 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (547)

Diseases linked to this target (Open Targets).

Spondyloenchondrodysplasia with immune dysregulation · score 0.82
genetic disorder · score 0.47
lysosomal storage disease · score 0.28
Alzheimer disease · score 0.28
neurodegenerative disease · score 0.28
Parkinson disease · score 0.28
multiple sclerosis · score 0.28
blood protein measurement · score 0.24
3-hydroxypropylmercapturic acid measurement · score 0.11
neoplasm · score 0.09

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-P13686-F1	alphafold	PREDICTED	94.63	—

Amino-acid sequence (325 residues)

MDMWTALLIL QALLLPSLAD GATPALRFVA VGDWGGVPNA PFHTAREMAN AKEIARTVQI LGADFILSLG DNFYFTGVQD INDKRFQETF EDVFSDRSLR KVPWYVLAGN HDHLGNVSAQ IAYSKISKRW NFPSPFYRLH FKIPQTNVSV AIFMLDTVTL CGNSDDFLSQ QPERPRDVKL ARTQLSWLKK QLAAAREDYV LVAGHYPVWS IAEHGPTHCL VKQLRPLLAT YGVTAYLCGH DHNLQYLQDE NGVGYVLSGA GNFMDPSKRH QRKVPNGYLR FHYGTEDSLG GFAYVEISSK EMTVTYIEAS GKSLFKTRLP RRARP

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards