About Cell adhesion molecule CEACAM1
Cell adhesion molecule CEACAM1 (CEACAM1) is a protein
from Homo sapiens identified by UniProt accession
P13688, 526 residues long.
MolForge cross-references it against 0 known binders and
342 disease associations.
Target properties
| Protein name | Cell adhesion molecule CEACAM1 |
|---|
| UniProt accession | P13688 |
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| Gene | CEACAM1 |
|---|
| Organism | Homo sapiens |
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| Length | 526 residues |
|---|
| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
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| Max clinical phase | — |
|---|
Disease associations (342)
Diseases linked to this target (Open Targets).
- breast adenocarcinoma · score 0.23
- pancreatic adenocarcinoma · score 0.22
- serum alanine aminotransferase measurement · score 0.20
- testosterone measurement · score 0.16
- head and neck squamous cell carcinoma · score 0.13
- neoplasm · score 0.12
- melanoma · score 0.12
- cancer · score 0.10
- hepatocellular carcinoma · score 0.09
- non-small cell lung carcinoma · score 0.09
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-P13688-F1 | alphafold | PREDICTED | 81.54 | — |
Amino-acid sequence (526 residues)
MGHLSAPLHR VRVPWQGLLL TASLLTFWNP PTTAQLTTES MPFNVAEGKE VLLLVHNLPQ QLFGYSWYKG ERVDGNRQIV GYAIGTQQAT PGPANSGRET IYPNASLLIQ NVTQNDTGFY TLQVIKSDLV NEEATGQFHV YPELPKPSIS SNNSNPVEDK DAVAFTCEPE TQDTTYLWWI NNQSLPVSPR LQLSNGNRTL TLLSVTRNDT GPYECEIQNP VSANRSDPVT LNVTYGPDTP TISPSDTYYR PGANLSLSCY AASNPPAQYS WLINGTFQQS TQELFIPNIT VNNSGSYTCH ANNSVTGCNR TTVKTIIVTE LSPVVAKPQI KASKTTVTGD KDSVNLTCST NDTGISIRWF FKNQSLPSSE RMKLSQGNTT LSINPVKRED AGTYWCEVFN PISKNQSDPI MLNVNYNALP QENGLSPGAI AGIVIGVVAL VALIAVALAC FLHFGKTGRA SDQRDLTEHK PSVSNHTQDH SNDPPNKMNE VTYSTLNFEA QQPTQPTSAS PSLTATEIIY SEVKKQ
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