About Oncostatin-M
Oncostatin-M (OSM) is a protein
from Homo sapiens identified by UniProt accession
P13725, 252 residues long.
MolForge cross-references it against 0 known binders and
316 disease associations.
Target properties
| Protein name | Oncostatin-M |
|---|
| UniProt accession | P13725 |
|---|
| Gene | OSM |
|---|
| Organism | Homo sapiens |
|---|
| Length | 252 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (316)
Diseases linked to this target (Open Targets).
- leukocyte count · score 0.26
- lung adenocarcinoma · score 0.21
- glioblastoma multiforme · score 0.19
- endometrial cancer · score 0.18
- myocardial infarction · score 0.17
- coronary artery disease · score 0.17
- gastric adenocarcinoma · score 0.15
- reticulocyte count · score 0.13
- reticulocyte measurement · score 0.13
- erythrocyte count · score 0.11
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-P13725-F1 | alphafold | PREDICTED | 78.75 | — |
Amino-acid sequence (252 residues)
MGVLLTQRTL LSLVLALLFP SMASMAAIGS CSKEYRVLLG QLQKQTDLMQ DTSRLLDPYI RIQGLDVPKL REHCRERPGA FPSEETLRGL GRRGFLQTLN ATLGCVLHRL ADLEQRLPKA QDLERSGLNI EDLEKLQMAR PNILGLRNNI YCMAQLLDNS DTAEPTKAGR GASQPPTPTP ASDAFQRKLE GCRFLHGYHR FMHSVGRVFS KWGESPNRSR RHSPHQALRK GVRRTRPSRK GKRLMTRGQL PR
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