About Annexin A8
Annexin A8 (ANXA8) is a protein
from Homo sapiens identified by UniProt accession
P13928, 327 residues long.
MolForge cross-references it against 0 known binders and
34 disease associations.
Target properties
| Protein name | Annexin A8 |
|---|
| UniProt accession | P13928 |
|---|
| Gene | ANXA8 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 327 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (34)
Diseases linked to this target (Open Targets).
- urinary bladder carcinoma · score 0.07
- alkaline phosphatase measurement · score 0.06
- esophageal adenocarcinoma · score 0.03
- neoplasm · score 0.03
- ovarian serous tumor · score 0.03
- cancer · score 0.02
- breast ductal carcinoma in situ · score 0.02
- ovarian carcinoma · score 0.02
- oral squamous cell carcinoma · score 0.02
- cervical squamous cell carcinoma · score 0.02
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-P13928-F1 | alphafold | PREDICTED | 94.44 | — |
Amino-acid sequence (327 residues)
MAWWKSWIEQ EGVTVKSSSH FNPDPDAETL YKAMKGIGTN EQAIIDVLTK RSNTQRQQIA KSFKAQFGKD LTETLKSELS GKFERLIVAL MYPPYRYEAK ELHDAMKGLG TKEGVIIEIL ASRTKNQLRE IMKAYEEDYG SSLEEDIQAD TSGYLERILV CLLQGSRDDV SSFVDPGLAL QDAQDLYAAG EKIRGTDEMK FITILCTRSA THLLRVFEEY EKIANKSIED SIKSETHGSL EEAMLTVVKC TQNLHSYFAE RLYYAMKGAG TRDGTLIRNI VSRSEIDLNL IKCHFKKMYG KTLSSMIMED TSGDYKNALL SLVGSDP
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