CD59 glycoprotein (CD59)

About CD59 glycoprotein

CD59 glycoprotein (CD59) is a protein from Homo sapiens identified by UniProt accession P13987, 128 residues long. MolForge cross-references it against 0 known binders and 661 disease associations.

Target properties

Protein name	CD59 glycoprotein
UniProt accession	P13987
Gene	CD59
Organism	Homo sapiens
Length	128 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (661)

Diseases linked to this target (Open Targets).

primary CD59 deficiency · score 0.76
blood protein measurement · score 0.39
dyskeratosis congenita, X-linked · score 0.37
blood phosphate measurement · score 0.26
chronotype measurement · score 0.25
genetic disorder · score 0.17
calcium measurement · score 0.15
cutaneous melanoma · score 0.14
diet measurement · score 0.12
neoplasm · score 0.10

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-P13987-F1	alphafold	PREDICTED	79.30	—

Amino-acid sequence (128 residues)

MGIQGGSVLF GLLLVLAVFC HSGHSLQCYN CPNPTADCKT AVNCSSDFDA CLITKAGLQV YNKCWKFEHC NFNDVTTRLR ENELTYYCCK KDLCNFNEQL ENGGTSLSEK TVLLLVTPFL AAAWSLHP

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards