About Folate receptor beta
Folate receptor beta (FOLR2) is a protein
from Homo sapiens identified by UniProt accession
P14207, 255 residues long.
MolForge cross-references it against 0 known binders and
90 disease associations.
Target properties
| Protein name | Folate receptor beta |
|---|
| UniProt accession | P14207 |
|---|
| Gene | FOLR2 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 255 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Approved drugs hitting this target (3)
DrugCentral-linked approved drugs that act on this protein.
Disease associations (90)
Diseases linked to this target (Open Targets).
- non-small cell lung carcinoma · score 0.08
- chronic kidney disease · score 0.07
- body height · score 0.07
- neoplasm · score 0.05
- Rheumatoid arthritis · score 0.04
- Barrett's esophagus · score 0.04
- diastolic blood pressure · score 0.04
- Acute hepatic failure · score 0.03
- acute lymphoblastic leukemia · score 0.02
- pelvic organ prolapse · score 0.02
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-P14207-F1 | alphafold | PREDICTED | 89.15 | — |
Amino-acid sequence (255 residues)
MVWKWMPLLL LLVCVATMCS AQDRTDLLNV CMDAKHHKTK PGPEDKLHDQ CSPWKKNACC TASTSQELHK DTSRLYNFNW DHCGKMEPAC KRHFIQDTCL YECSPNLGPW IQQVNQSWRK ERFLDVPLCK EDCQRWWEDC HTSHTCKSNW HRGWDWTSGV NKCPAGALCR TFESYFPTPA ALCEGLWSHS YKVSNYSRGS GRCIQMWFDS AQGNPNEEVA RFYAAAMHVN AGEMLHGTGG LLLSLALMLQ LWLLG
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