About CD99 antigen
CD99 antigen (CD99) is a protein
from Homo sapiens identified by UniProt accession
P14209, 185 residues long.
MolForge cross-references it against 0 known binders and
21 disease associations.
Target properties
| Protein name | CD99 antigen |
|---|
| UniProt accession | P14209 |
|---|
| Gene | CD99 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 185 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (21)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.25
- breast adenocarcinoma · score 0.18
- primary ovarian insufficiency · score 0.12
- head and neck squamous cell carcinoma · score 0.11
- glioblastoma multiforme · score 0.02
- astrocytoma · score 0.01
- ovarian carcinoma · score 0.01
- clear cell renal carcinoma · score 0.01
- breast carcinoma · score 0.01
- pituitary cancer · score 0.01
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-P14209-F1 | alphafold | PREDICTED | 60.86 | — |
Amino-acid sequence (185 residues)
MARGAALALL LFGLLGVLVA APDGGFDLSD ALPDNENKKP TAIPKKPSAG DDFDLGDAVV DGENDDPRPP NPPKPMPNPN PNHPSSSGSF SDADLADGVS GGEGKGGSDG GGSHRKEGEE ADAPGVIPGI VGAVVVAVAG AISSFIAYQK KKLCFKENAE QGEVDMESHR NANAEPAVQR TLLEK
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