Carboxypeptidase M (CPM)

About Carboxypeptidase M

Carboxypeptidase M (CPM) is a protein from Homo sapiens identified by UniProt accession P14384, 443 residues long. MolForge cross-references it against 0 known binders and 63 disease associations.

Target properties

Protein name	Carboxypeptidase M
UniProt accession	P14384
Gene	CPM
Organism	Homo sapiens
Length	443 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (63)

Diseases linked to this target (Open Targets).

traffic air pollution measurement · score 0.29
pneumoconiosis · score 0.19
erythrocyte count · score 0.06
mean corpuscular volume · score 0.06
mean corpuscular hemoglobin · score 0.05
myeloid white cell count · score 0.04
leukocyte count · score 0.04
red blood cell density measurement · score 0.04
mean corpuscular hemoglobin concentration · score 0.04
lymphocyte count · score 0.04

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-P14384-F1	alphafold	PREDICTED	90.30	—

Amino-acid sequence (443 residues)

MDFPCLWLGL LLPLVAALDF NYHRQEGMEA FLKTVAQNYS SVTHLHSIGK SVKGRNLWVL VVGRFPKEHR IGIPEFKYVA NMHGDETVGR ELLLHLIDYL VTSDGKDPEI TNLINSTRIH IMPSMNPDGF EAVKKPDCYY SIGRENYNQY DLNRNFPDAF EYNNVSRQPE TVAVMKWLKT ETFVLSANLH GGALVASYPF DNGVQATGAL YSRSLTPDDD VFQYLAHTYA SRNPNMKKGD ECKNKMNFPN GVTNGYSWYP LQGGMQDYNY IWAQCFEITL ELSCCKYPRE EKLPSFWNNN KASLIEYIKQ VHLGVKGQVF DQNGNPLPNV IVEVQDRKHI CPYRTNKYGE YYLLLLPGSY IINVTVPGHD PHITKVIIPE KSQNFSALKK DILLPFQGQL DSIPVSNPSC PMIPLYRNLP DHSAATKPSL FLFLVSLLHI FFK

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards