Cytochrome c oxidase subunit 7A2, mitochondrial…

About Cytochrome c oxidase subunit 7A2, mitochondrial

Cytochrome c oxidase subunit 7A2, mitochondrial (COX7A2) is a protein from Homo sapiens identified by UniProt accession P14406, 83 residues long. MolForge cross-references it against 0 known binders and 37 disease associations.

Target properties

Protein name	Cytochrome c oxidase subunit 7A2, mitochondrial
UniProt accession	P14406
Gene	COX7A2
Organism	Homo sapiens
Length	83 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (37)

Diseases linked to this target (Open Targets).

protein measurement · score 0.04
cortical thickness · score 0.04
vital capacity · score 0.03
HIV infection · score 0.02
appendicular lean mass · score 0.02
Abnormal sperm morphology · score 0.02
bacteriemia · score 0.02
Barrett adenocarcinoma · score 0.01
microphthalmia with limb anomalies · score 0.01
neoplasm · score 0.01

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-P14406-F1	alphafold	PREDICTED	88.44	—

Amino-acid sequence (83 residues)

MLRNLLALRQ IGQRTISTAS RRHFKNKVPE KQKLFQEDDE IPLYLKGGVA DALLYRATMI LTVGGTAYAI YELAVASFPK KQE

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards

Cytochrome c oxidase subunit 7A2, mitochondrial (COX7A2)