Acylphosphatase-2 (ACYP2)

About Acylphosphatase-2

Acylphosphatase-2 (ACYP2) is a protein from Homo sapiens identified by UniProt accession P14621, 99 residues long. MolForge cross-references it against 0 known binders and 89 disease associations.

Target properties

Protein name	Acylphosphatase-2
UniProt accession	P14621
Gene	ACYP2
Organism	Homo sapiens
Length	99 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (89)

Diseases linked to this target (Open Targets).

circadian rhythm · score 0.39
blood protein measurement · score 0.38
osteomyelitis · score 0.33
body height · score 0.32
protein measurement · score 0.31
sudden cardiac arrest · score 0.30
Abnormal bleeding · score 0.30
physical activity measurement · score 0.29
lymphocyte percentage of leukocytes · score 0.28
heel bone mineral density · score 0.27

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-P14621-F1	alphafold	PREDICTED	95.69	—

Amino-acid sequence (99 residues)

MSTAQSLKSV DYEVFGRVQG VCFRMYTEDE ARKIGVVGWV KNTSKGTVTG QVQGPEDKVN SMKSWLSKVG SPSSRIDRTN FSNEKTISKL EYSNFSIRY

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards