About Myosin light chain 6B
Myosin light chain 6B (MYL6B) is a protein
from Homo sapiens identified by UniProt accession
P14649, 208 residues long.
MolForge cross-references it against 0 known binders and
30 disease associations.
Target properties
| Protein name | Myosin light chain 6B |
|---|
| UniProt accession | P14649 |
|---|
| Gene | MYL6B |
|---|
| Organism | Homo sapiens |
|---|
| Length | 208 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (30)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.37
- Alzheimer disease · score 0.33
- Parkinson disease · score 0.33
- multiple sclerosis · score 0.33
- lysosomal storage disease · score 0.33
- hepatocellular carcinoma · score 0.09
- rectal adenocarcinoma · score 0.08
- appendicular lean mass · score 0.05
- Inguinal hernia · score 0.03
- neoplasm · score 0.03
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-P14649-F1 | alphafold | PREDICTED | 81.94 | — |
Amino-acid sequence (208 residues)
MPPKKDVPVK KPAGPSISKP AAKPAAAGAP PAKTKAEPAV PQAPQKTQEP PVDLSKVVIE FNKDQLEEFK EAFELFDRVG DGKILYSQCG DVMRALGQNP TNAEVLKVLG NPKSDELKSR RVDFETFLPM LQAVAKNRGQ GTYEDYLEGF RVFDKEGNGK VMGAELRHVL TTLGEKMTEE EVETVLAGHE DSNGCINYEA FLKHILSV
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