About Homeobox protein Hox-B2
Homeobox protein Hox-B2 (HOXB2) is a protein
from Homo sapiens identified by UniProt accession
P14652, 356 residues long.
MolForge cross-references it against 0 known binders and
110 disease associations.
Target properties
| Protein name | Homeobox protein Hox-B2 |
|---|
| UniProt accession | P14652 |
|---|
| Gene | HOXB2 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 356 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (110)
Diseases linked to this target (Open Targets).
- breast adenocarcinoma · score 0.22
- motion sickness · score 0.18
- head and neck squamous cell carcinoma · score 0.15
- BMI-adjusted waist circumference · score 0.15
- appendicular lean mass · score 0.15
- FEV/FVC ratio · score 0.15
- cortical surface area measurement · score 0.10
- insomnia measurement · score 0.10
- snoring measurement · score 0.08
- breast cancer · score 0.08
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-P14652-F1 | alphafold | PREDICTED | 60.15 | — |
Amino-acid sequence (356 residues)
MNFEFEREIG FINSQPSLAE CLTSFPAVLE TFQTSSIKES TLIPPPPPFE QTFPSLQPGA STLQRPRSQK RAEDGPALPP PPPPPLPAAP PAPEFPWMKE KKSAKKPSQS ATSPSPAASA VPASGVGSPA DGLGLPEAGG GGARRLRTAY TNTQLLELEK EFHFNKYLCR PRRVEIAALL DLTERQVKVW FQNRRMKHKR QTQHREPPDG EPACPGALED ICDPAEEPAA SPGGPSASRA AWEACCHPPE VVPGALSADP RPLAVRLEGA GASSPGCALR GAGGLEPGPL PEDVFSGRQD SPFLPDLNFF AADSCLQLSG GLSPSLQGSL DSPVPFSEEE LDFFTSTLCA IDLQFP
Explore Homeobox protein Hox-B2 with MolForge
Find binders, run structure-based screening, and map this target across
diseases and approved drugs with our AI-powered platform.
Browse all targets