About Platelet glycoprotein IX
Platelet glycoprotein IX (GP9) is a protein
from Homo sapiens identified by UniProt accession
P14770, 177 residues long.
MolForge cross-references it against 0 known binders and
114 disease associations.
Target properties
| Protein name | Platelet glycoprotein IX |
|---|
| UniProt accession | P14770 |
|---|
| Gene | GP9 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 177 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (114)
Diseases linked to this target (Open Targets).
- Bernard-Soulier syndrome · score 0.80
- platelet component distribution width · score 0.50
- platelet count · score 0.50
- mean platelet volume · score 0.50
- platelet crit · score 0.47
- Macrothrombocytopenia · score 0.46
- Thrombocytopenia · score 0.30
- cutaneous melanoma · score 0.20
- squamous cell lung carcinoma · score 0.19
- genetic disorder · score 0.18
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-P14770-F1 | alphafold | PREDICTED | 84.67 | — |
Amino-acid sequence (177 residues)
MPAWGALFLL WATAEATKDC PSPCTCRALE TMGLWVDCRG HGLTALPALP ARTRHLLLAN NSLQSVPPGA FDHLPQLQTL DVTQNPWHCD CSLTYLRLWL EDRTPEALLQ VRCASPSLAA HGPLGRLTGY QLGSCGWQLQ ASWVRPGVLW DVALVAVAAL GLALLAGLLC ATTEALD
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