Carboxypeptidase B (CPB1)

About Carboxypeptidase B

Carboxypeptidase B (CPB1) is a protein from Homo sapiens identified by UniProt accession P15086, 417 residues long. MolForge cross-references it against 0 known binders and 176 disease associations.

Target properties

Protein name	Carboxypeptidase B
UniProt accession	P15086
Gene	CPB1
Organism	Homo sapiens
Length	417 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (176)

Diseases linked to this target (Open Targets).

neuroinflammatory disorder · score 0.30
blood protein measurement · score 0.29
protein measurement · score 0.29
mean corpuscular hemoglobin concentration · score 0.21
endometrial cancer · score 0.18
pancreatic adenocarcinoma · score 0.16
cutaneous melanoma · score 0.13
squamous cell lung carcinoma · score 0.10
head and neck squamous cell carcinoma · score 0.10
adolescent idiopathic scoliosis · score 0.09

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-P15086-F1	alphafold	PREDICTED	95.34	—

Amino-acid sequence (417 residues)

MLALLVLVTV ALASAHHGGE HFEGEKVFRV NVEDENHINI IRELASTTQI DFWKPDSVTQ IKPHSTVDFR VKAEDTVTVE NVLKQNELQY KVLISNLRNV VEAQFDSRVR ATGHSYEKYN KWETIEAWTQ QVATENPALI SRSVIGTTFE GRAIYLLKVG KAGQNKPAIF MDCGFHAREW ISPAFCQWFV REAVRTYGRE IQVTELLDKL DFYVLPVLNI DGYIYTWTKS RFWRKTRSTH TGSSCIGTDP NRNFDAGWCE IGASRNPCDE TYCGPAAESE KETKALADFI RNKLSSIKAY LTIHSYSQMM IYPYSYAYKL GENNAELNAL AKATVKELAS LHGTKYTYGP GATTIYPAAG GSDDWAYDQG IRYSFTFELR DTGRYGFLLP ESQIRATCEE TFLAIKYVAS YVLEHLY

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards