Interleukin-9 (IL9)

About Interleukin-9

Interleukin-9 (IL9) is a protein from Homo sapiens identified by UniProt accession P15248, 144 residues long. MolForge cross-references it against 0 known binders and 540 disease associations.

Target properties

Protein name	Interleukin-9
UniProt accession	P15248
Gene	IL9
Organism	Homo sapiens
Length	144 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (540)

Diseases linked to this target (Open Targets).

eosinophil count · score 0.47
neurodegenerative disease · score 0.40
eosinophil percentage of leukocytes · score 0.30
pancreatic adenocarcinoma · score 0.23
neoplasm · score 0.16
asthma · score 0.11
sphingomyelin measurement · score 0.11
Rheumatoid arthritis · score 0.11
experimental autoimmune encephalomyelitis · score 0.10
allergic rhinitis · score 0.10

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-P15248-F1	alphafold	PREDICTED	84.09	—

Amino-acid sequence (144 residues)

MLLAMVLTSA LLLCSVAGQG CPTLAGILDI NFLINKMQED PASKCHCSAN VTSCLCLGIP SDNCTRPCFS ERLSQMTNTT MQTRYPLIFS RVKKSVEVLK NNKCPYFSCE QPCNQTTAGN ALTFLKSLLE IFQKEKMRGM RGKI

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards