Prostatic acid phosphatase (ACP3)

About Prostatic acid phosphatase

Prostatic acid phosphatase (ACP3) is a protein from Homo sapiens identified by UniProt accession P15309, 386 residues long. MolForge cross-references it against 0 known binders and 194 disease associations.

Target properties

Protein name	Prostatic acid phosphatase
UniProt accession	P15309
Gene	ACP3
Organism	Homo sapiens
Length	386 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Approved drugs hitting this target (1)

DrugCentral-linked approved drugs that act on this protein.

Disease associations (194)

Diseases linked to this target (Open Targets).

prostate cancer · score 0.50
neoplasm · score 0.40
hematocrit · score 0.37
self reported educational attainment · score 0.33
serum albumin measurement · score 0.31
Red cell distribution width · score 0.31
prostate adenocarcinoma · score 0.30
hemoglobin measurement · score 0.23
creatinine measurement · score 0.16
total cholesterol measurement · score 0.16

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-P15309-F1	alphafold	PREDICTED	92.24	—

Amino-acid sequence (386 residues)

MRAAPLLLAR AASLSLGFLF LLFFWLDRSV LAKELKFVTL VFRHGDRSPI DTFPTDPIKE SSWPQGFGQL TQLGMEQHYE LGEYIRKRYR KFLNESYKHE QVYIRSTDVD RTLMSAMTNL AALFPPEGVS IWNPILLWQP IPVHTVPLSE DQLLYLPFRN CPRFQELESE TLKSEEFQKR LHPYKDFIAT LGKLSGLHGQ DLFGIWSKVY DPLYCESVHN FTLPSWATED TMTKLRELSE LSLLSLYGIH KQKEKSRLQG GVLVNEILNH MKRATQIPSY KKLIMYSAHD TTVSGLQMAL DVYNGLLPPY ASCHLTELYF EKGEYFVEMY YRNETQHEPY PLMLPGCSPS CPLERFAELV GPVIPQDWST ECMTTNSHQG TEDSTD

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards