Potassium voltage-gated channel subfamily E member 1 (KCNE1)

About Potassium voltage-gated channel subfamily E member 1

Potassium voltage-gated channel subfamily E member 1 (KCNE1) is a protein from Homo sapiens identified by UniProt accession P15382, 129 residues long. MolForge cross-references it against 0 known binders and 225 disease associations.

Target properties

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Disease associations (225)

Diseases linked to this target (Open Targets).

• long QT syndrome 5 · score 0.81
• Jervell and Lange-Nielsen syndrome 2 · score 0.77
• Romano-Ward syndrome · score 0.75
• Prolonged QT interval · score 0.55
• Abnormality of the cardiovascular system · score 0.50
• Jervell and Lange-Nielsen syndrome · score 0.45
• QT interval · score 0.43
• electrocardiography · score 0.39
• familial long QT syndrome · score 0.37
• neuroinflammatory disorder · score 0.33

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Amino-acid sequence (129 residues)

External references