About B-lymphocyte antigen CD19
B-lymphocyte antigen CD19 (CD19) is a protein
from Homo sapiens identified by UniProt accession
P15391, 556 residues long.
MolForge cross-references it against 0 known binders and
1,014 disease associations.
Target properties
| Protein name | B-lymphocyte antigen CD19 |
|---|
| UniProt accession | P15391 |
|---|
| Gene | CD19 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 556 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Approved drugs hitting this target (4)
DrugCentral-linked approved drugs that act on this protein.
Disease associations (1014)
Diseases linked to this target (Open Targets).
- common variable immunodeficiency · score 0.71
- diffuse large B-cell lymphoma · score 0.59
- acute lymphoblastic leukemia · score 0.55
- neuromyelitis optica · score 0.54
- neoplasm · score 0.54
- lymphoid leukemia · score 0.52
- follicular lymphoma · score 0.49
- B-cell acute lymphoblastic leukemia · score 0.49
- recurrent infections associated with rare immunoglobulin isotypes deficiency · score 0.48
- agammaglobulinemia · score 0.47
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-P15391-F1 | alphafold | PREDICTED | 62.22 | — |
Amino-acid sequence (556 residues)
MPPPRLLFFL LFLTPMEVRP EEPLVVKVEE GDNAVLQCLK GTSDGPTQQL TWSRESPLKP FLKLSLGLPG LGIHMRPLAI WLFIFNVSQQ MGGFYLCQPG PPSEKAWQPG WTVNVEGSGE LFRWNVSDLG GLGCGLKNRS SEGPSSPSGK LMSPKLYVWA KDRPEIWEGE PPCLPPRDSL NQSLSQDLTM APGSTLWLSC GVPPDSVSRG PLSWTHVHPK GPKSLLSLEL KDDRPARDMW VMETGLLLPR ATAQDAGKYY CHRGNLTMSF HLEITARPVL WHWLLRTGGW KVSAVTLAYL IFCLCSLVGI LHLQRALVLR RKRKRMTDPT RRFFKVTPPP GSGPQNQYGN VLSLPTPTSG LGRAQRWAAG LGGTAPSYGN PSSDVQADGA LGSRSPPGVG PEEEEGEGYE EPDSEEDSEF YENDSNLGQD QLSQDGSGYE NPEDEPLGPE DEDSFSNAES YENEDEELTQ PVARTMDFLS PHGSAWDPSR EATSLGSQSY EDMRGILYAA PQLRSIRGQP GPNHEEDADS YENMDNPDGP DPAWGGGGRM GTWSTR
Explore B-lymphocyte antigen CD19 with MolForge
Find binders, run structure-based screening, and map this target across
diseases and approved drugs with our AI-powered platform.
Browse all targets