Glycophorin-E (GYPE)

About Glycophorin-E

Glycophorin-E (GYPE) is a protein from Homo sapiens identified by UniProt accession P15421, 78 residues long. MolForge cross-references it against 0 known binders and 138 disease associations.

Target properties

Protein name	Glycophorin-E
UniProt accession	P15421
Gene	GYPE
Organism	Homo sapiens
Length	78 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (138)

Diseases linked to this target (Open Targets).

Red cell distribution width · score 0.39
lymphocyte percentage of leukocytes · score 0.30
platelet crit · score 0.29
blood protein measurement · score 0.26
reticulocyte count · score 0.26
chronic obstructive pulmonary disease · score 0.22
smoking status measurement · score 0.18
platelet count · score 0.16
bilirubin measurement · score 0.16
mean corpuscular volume · score 0.16

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-P15421-F1	alphafold	PREDICTED	69.74	—

Amino-acid sequence (78 residues)

MYGKIIFVLL LSGIVSISAS STTGVAMHTS TSSSVTKSYI SSQTNGITLI NWWAMARVIF EVMLVVVGMI ILISYCIR

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards