Histatin-1 (HTN1)

About Histatin-1

Histatin-1 (HTN1) is a protein from Homo sapiens identified by UniProt accession P15515, 57 residues long. MolForge cross-references it against 0 known binders and 34 disease associations.

Target properties

Protein name	Histatin-1
UniProt accession	P15515
Gene	HTN1
Organism	Homo sapiens
Length	57 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (34)

Diseases linked to this target (Open Targets).

endometrial cancer · score 0.15
dental caries · score 0.03
microphthalmia with limb anomalies · score 0.03
Obesity · score 0.02
cancer · score 0.02
pulse pressure measurement · score 0.02
neoplasm · score 0.02
Peri-Implantitis · score 0.01
enamel caries · score 0.01
mucous membrane pemphigoid · score 0.01

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-P15515-F1	alphafold	PREDICTED	63.16	—

Amino-acid sequence (57 residues)

MKFFVFALVL ALMISMISAD SHEKRHHGYR RKFHEKHHSH REFPFYGDYG SNYLYDN

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards