Membrane cofactor protein (CD46)

About Membrane cofactor protein

Membrane cofactor protein (CD46) is a protein from Homo sapiens identified by UniProt accession P15529, 392 residues long. MolForge cross-references it against 0 known binders and 416 disease associations.

Target properties

Protein name	Membrane cofactor protein
UniProt accession	P15529
Gene	CD46
Organism	Homo sapiens
Length	392 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-P15529-F1	alphafold	PREDICTED	82.13	—

Amino-acid sequence (392 residues)

MEPPGRRECP FPSWRFPGLL LAAMVLLLYS FSDACEEPPT FEAMELIGKP KPYYEIGERV DYKCKKGYFY IPPLATHTIC DRNHTWLPVS DDACYRETCP YIRDPLNGQA VPANGTYEFG YQMHFICNEG YYLIGEEILY CELKGSVAIW SGKPPICEKV LCTPPPKIKN GKHTFSEVEV FEYLDAVTYS CDPAPGPDPF SLIGESTIYC GDNSVWSRAA PECKVVKCRF PVVENGKQIS GFGKKFYYKA TVMFECDKGF YLDGSDTIVC DSNSTWDPPV PKCLKVLPPS STKPPALSHS VSTSSTTKSP ASSASGPRPT YKPPVSNYPG YPKPEEGILD SLDVWVIAVI VIAIVVGVAV ICVVPYRYLQ RRKKKGTYLT DETHREVKFT SL

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards