About Zinc finger protein 44
Zinc finger protein 44 (ZNF44) is a protein
from Homo sapiens identified by UniProt accession
P15621, 663 residues long.
MolForge cross-references it against 0 known binders and
18 disease associations.
Target properties
| Protein name | Zinc finger protein 44 |
|---|
| UniProt accession | P15621 |
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| Gene | ZNF44 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 663 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (18)
Diseases linked to this target (Open Targets).
- Down syndrome · score 0.04
- mean corpuscular volume · score 0.04
- neuroblastoma · score 0.01
- neuroendocrine neoplasm · score 0.01
- neoplasm · score 0.01
- ependymoma · score 0.00
- Pick disease · score 0.00
- oligodendroglioma · score 0.00
- HIV infection · score 0.00
- glioblastoma multiforme · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-P15621-F1 | alphafold | PREDICTED | 65.98 | — |
Amino-acid sequence (663 residues)
MALCYGTFWG YPKMLEAANL MEGLVDIGPW VTLPRGQPEV LEWGLPKDQD SVAFEDVAVN FTHEEWALLG PSQKNLYRDV MRETIRNLNC IGMKWENQNI DDQHQNLRRN PRCDVVERFG KSKDGSQCGE TLSQIRNSIV NKNTPARVDA CGSSVNGEVI MGHSSLNCYI RVDTGHKHRE CHEYAEKSYT HKQCGKGLSY RHSFQTCERP HTGKKPYDCK ECGKTFSSPG NLRRHMVVKG GDGPYKCELC GKAFFWPSLL RMHERTHTGE KPYECKQCSK AFPVYSSYLR HEKIHTGEKP YECKQCSKAF PDYSSYLRHE RTHTGEKPYK CKQCGKAFSV SGSLRVHERI HTGEKPYTCK QCGKAFCHLG SFQRHMIMHS GDGPHKCKIC GKGFDFPGSA RIHEGTHTLE KPYECKQCGK LLSHRSSFRR HMMAHTGDGP HKCTVCGKAF DSPSVFQRHE RTHTGEKPYE CKQCGKAFRT SSSLRKHETT HTGEQPYKCK CGKAFSDLFS FQSHETTHSE EEPYECKECG KAFSSFKYFC RHERTHSEEK SYECQICGKA FSRFSYLKTH ERTHTAEKPY ECKQCRKAFF WPSFLLRHER THTGERPYEC KHCGKAFSRS SFCREHERTH TGEKPYECKE CGKAFSSLSS FNRHKRTHWK DIL
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