About Vascular endothelial growth factor A, long form
Vascular endothelial growth factor A, long form (VEGFA) is a protein
from Homo sapiens identified by UniProt accession
P15692, 395 residues long.
MolForge cross-references it against 0 known binders and
2,722 disease associations.
Target properties
| Protein name | Vascular endothelial growth factor A, long form |
|---|
| UniProt accession | P15692 |
|---|
| Gene | VEGFA |
|---|
| Organism | Homo sapiens |
|---|
| Length | 395 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Approved drugs hitting this target (9)
DrugCentral-linked approved drugs that act on this protein.
Disease associations (2722)
Diseases linked to this target (Open Targets).
- diabetic retinopathy · score 0.70
- age-related macular degeneration · score 0.68
- wet macular degeneration · score 0.65
- diabetic macular edema · score 0.63
- macular retinal edema · score 0.61
- hepatocellular carcinoma · score 0.61
- non-small cell lung carcinoma · score 0.61
- proliferative diabetic retinopathy · score 0.61
- breast cancer · score 0.61
- retinal vein occlusion · score 0.60
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-P15692-F1 | alphafold | PREDICTED | 63.91 | — |
Amino-acid sequence (395 residues)
MTDRQTDTAP SPSYHLLPGR RRTVDAAASR GQGPEPAPGG GVEGVGARGV ALKLFVQLLG CSRFGGAVVR AGEAEPSGAA RSASSGREEP QPEEGEEEEE KEEERGPQWR LGARKPGSWT GEAAVCADSA PAARAPQALA RASGRGGRVA RRGAEESGPP HSPSRRGSAS RAGPGRASET MNFLLSWVHW SLALLLYLHH AKWSQAAPMA EGGGQNHHEV VKFMDVYQRS YCHPIETLVD IFQEYPDEIE YIFKPSCVPL MRCGGCCNDE GLECVPTEES NITMQIMRIK PHQGQHIGEM SFLQHNKCEC RPKKDRARQE KKSVRGKGKG QKRKRKKSRY KSWSVPCGPC SERRKHLFVQ DPQTCKCSCK NTDSRCKARQ LELNERTCRC DKPRR
Explore Vascular endothelial growth factor A, long form with MolForge
Find binders, run structure-based screening, and map this target across
diseases and approved drugs with our AI-powered platform.
Browse all targets