T-cell surface glycoprotein CD1e…

About T-cell surface glycoprotein CD1e, membrane-associated

T-cell surface glycoprotein CD1e, membrane-associated (CD1E) is a protein from Homo sapiens identified by UniProt accession P15812, 388 residues long. MolForge cross-references it against 0 known binders and 42 disease associations.

Target properties

Protein name	T-cell surface glycoprotein CD1e, membrane-associated
UniProt accession	P15812
Gene	CD1E
Organism	Homo sapiens
Length	388 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (42)

Diseases linked to this target (Open Targets).

neurodegenerative disease · score 0.37
Guillain-Barre syndrome · score 0.07
lung adenocarcinoma · score 0.06
QRS duration · score 0.04
COVID-19 · score 0.04
sphingomyelin measurement · score 0.04
mean corpuscular volume · score 0.03
reticulocyte measurement · score 0.03
neoplasm · score 0.02
myeloid sarcoma · score 0.01

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-P15812-F1	alphafold	PREDICTED	81.52	—

Amino-acid sequence (388 residues)

MLLLFLLFEG LCCPGENTAA PQALQSYHLA AEEQLSFRML QTSSFANHSW AHSEGSGWLG DLQTHGWDTV LGTIRFLKPW SHGNFSKQEL KNLQSLFQLY FHSFIQIVQA SAGQFQLEYP FEIQILAGCR MNAPQIFLNM AYQGSDFLSF QGISWEPSPG AGIRAQNICK VLNRYLDIKE ILQSLLGHTC PRFLAGLMEA GESELKRKVK PEAWLSCGPS PGPGRLQLVC HVSGFYPKPV WVMWMRGEQE QRGTQRGDVL PNADETWYLR ATLDVAAGEA AGLSCRVKHS SLGGHDLIIH WGGYSIFLIL ICLTVIVTLV ILVVVDSRLK KQSSNKNILS PHTPSPVFLM GANTQDTKNS RHQFCLAQVS WIKNRVLKKW KTRLNQLW

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards

T-cell surface glycoprotein CD1e, membrane-associated (CD1E)