Antigen-presenting glycoprotein CD1d (CD1D)

About Antigen-presenting glycoprotein CD1d

Antigen-presenting glycoprotein CD1d (CD1D) is a protein from Homo sapiens identified by UniProt accession P15813, 335 residues long. MolForge cross-references it against 0 known binders and 596 disease associations.

Target properties

Protein name	Antigen-presenting glycoprotein CD1d
UniProt accession	P15813
Gene	CD1D
Organism	Homo sapiens
Length	335 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (596)

Diseases linked to this target (Open Targets).

leukocyte count · score 0.26
neutrophil count · score 0.26
neoplasm · score 0.12
chronic lymphocytic leukemia · score 0.10
Systemic lupus erythematosus · score 0.09
acute lymphoblastic leukemia · score 0.08
acute myeloid leukemia · score 0.08
myeloid sarcoma · score 0.08
isolated agammaglobulinemia · score 0.08
Red cell distribution width · score 0.08

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-P15813-F1	alphafold	PREDICTED	89.91	—

Amino-acid sequence (335 residues)

MGCLLFLLLW ALLQAWGSAE VPQRLFPLRC LQISSFANSS WTRTDGLAWL GELQTHSWSN DSDTVRSLKP WSQGTFSDQQ WETLQHIFRV YRSSFTRDVK EFAKMLRLSY PLELQVSAGC EVHPGNASNN FFHVAFQGKD ILSFQGTSWE PTQEAPLWVN LAIQVLNQDK WTRETVQWLL NGTCPQFVSG LLESGKSELK KQVKPKAWLS RGPSPGPGRL LLVCHVSGFY PKPVWVKWMR GEQEQQGTQP GDILPNADET WYLRATLDVV AGEAAGLSCR VKHSSLEGQD IVLYWGGSYT SMGLIALAVL ACLLFLLIVG FTSRFKRQTS YQGVL

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards