Cytochrome c oxidase subunit 7C, mitochondrial (COX7C)

About Cytochrome c oxidase subunit 7C, mitochondrial

Cytochrome c oxidase subunit 7C, mitochondrial (COX7C) is a protein from Homo sapiens identified by UniProt accession P15954, 63 residues long. MolForge cross-references it against 0 known binders and 54 disease associations.

Target properties

Protein name	Cytochrome c oxidase subunit 7C, mitochondrial
UniProt accession	P15954
Gene	COX7C
Organism	Homo sapiens
Length	63 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (54)

Diseases linked to this target (Open Targets).

neurodegenerative disease · score 0.56
Parkinson disease · score 0.37
Alzheimer disease · score 0.37
multiple sclerosis · score 0.37
neuroinflammatory disorder · score 0.37
lysosomal storage disease · score 0.37
glioblastoma multiforme · score 0.23
endometrial cancer · score 0.18
body mass index · score 0.16
ulcer of lower limb · score 0.13

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-P15954-F1	alphafold	PREDICTED	91.40	—

Amino-acid sequence (63 residues)

MLGQSIRRFT TSVVRRSHYE EGPGKNLPFS VENKWSLLAK MCLYFGSAFA TPFLVVRHQL LKT

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards