About Mitochondrial coenzyme A transporter SLC25A16
Mitochondrial coenzyme A transporter SLC25A16 (SLC25A16) is a protein
from Homo sapiens identified by UniProt accession
P16260, 332 residues long.
MolForge cross-references it against 0 known binders and
117 disease associations.
Target properties
| Protein name | Mitochondrial coenzyme A transporter SLC25A16 |
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| UniProt accession | P16260 |
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| Gene | SLC25A16 |
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| Organism | Homo sapiens |
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| Length | 332 residues |
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| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
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| Druggability score | — |
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| Pocket score | — |
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| Max clinical phase | — |
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Disease associations (117)
Diseases linked to this target (Open Targets).
- Isolated nail anomaly · score 0.33
- inherited isolated nail anomaly · score 0.33
- Rare genetic intellectual disability with developmental anomaly · score 0.27
- lean body mass · score 0.22
- fat body mass · score 0.17
- whole body water mass · score 0.15
- base metabolic rate measurement · score 0.11
- BMI-adjusted hip circumference · score 0.11
- alkaline phosphatase measurement · score 0.08
- body height · score 0.05
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-P16260-F1 | alphafold | PREDICTED | 83.83 | — |
Amino-acid sequence (332 residues)
MAAATAAAAL AAADPPPAMP QAAGAGGPTT RRDFYWLRSF LAGGIAGCCA KTTVAPLDRV KVLLQAHNHH YKHLGVFSAL RAVPQKEGFL GLYKGNGAMM IRIFPYGAIQ FMAFEHYKTL ITTKLGISGH VHRLMAGSMA GMTAVICTYP LDMVRVRLAF QVKGEHSYTG IIHAFKTIYA KEGGFFGFYR GLMPTILGMA PYAGVSFFTF GTLKSVGLSH APTLLGRPSS DNPNVLVLKT HVNLLCGGVA GAIAQTISYP FDVTRRRMQL GTVLPEFEKC LTMRDTMKYV YGHHGIRKGL YRGLSLNYIR CIPSQAVAFT TYELMKQFFH LN
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