About Histone H1.3
Histone H1.3 (H1-3) is a protein
from Homo sapiens identified by UniProt accession
P16402, 221 residues long.
MolForge cross-references it against 0 known binders and
62 disease associations.
Target properties
| Protein name | Histone H1.3 |
|---|
| UniProt accession | P16402 |
|---|
| Gene | H1-3 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 221 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (62)
Diseases linked to this target (Open Targets).
- platelet-to-lymphocyte ratio · score 0.09
- body fat percentage · score 0.08
- breast carcinoma · score 0.08
- actinic keratosis · score 0.07
- body height · score 0.07
- gout · score 0.06
- sebaceous of Jadassohn nevus · score 0.06
- self reported educational attainment · score 0.05
- drug use measurement · score 0.05
- sex hormone-binding globulin measurement · score 0.05
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-P16402-F1 | alphafold | PREDICTED | 63.91 | — |
Amino-acid sequence (221 residues)
MSETAPLAPT IPAPAEKTPV KKKAKKAGAT AGKRKASGPP VSELITKAVA ASKERSGVSL AALKKALAAA GYDVEKNNSR IKLGLKSLVS KGTLVQTKGT GASGSFKLNK KAASGEGKPK AKKAGAAKPR KPAGAAKKPK KVAGAATPKK SIKKTPKKVK KPATAAGTKK VAKSAKKVKT PQPKKAAKSP AKAKAPKPKA AKPKSGKPKV TKAKKAAPKK K
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