About UDP-glucuronosyltransferase 2B7
UDP-glucuronosyltransferase 2B7 (UGT2B7) is a protein
from Homo sapiens identified by UniProt accession
P16662, 529 residues long.
MolForge cross-references it against 0 known binders and
109 disease associations.
Target properties
| Protein name | UDP-glucuronosyltransferase 2B7 |
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| UniProt accession | P16662 |
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| Gene | UGT2B7 |
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| Organism | Homo sapiens |
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| Length | 529 residues |
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| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
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| Druggability score | — |
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| Pocket score | — |
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| Max clinical phase | — |
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Disease associations (109)
Diseases linked to this target (Open Targets).
- response to tramadol · score 0.54
- vitamin D measurement · score 0.51
- testosterone measurement · score 0.47
- systolic blood pressure · score 0.46
- alkaline phosphatase measurement · score 0.44
- serum gamma-glutamyl transferase measurement · score 0.40
- estradiol measurement · score 0.36
- low density lipoprotein cholesterol measurement · score 0.35
- blood phosphate measurement · score 0.33
- urinary metabolite measurement · score 0.32
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-P16662-F1 | alphafold | PREDICTED | 93.32 | — |
Amino-acid sequence (529 residues)
MSVKWTSVIL LIQLSFCFSS GNCGKVLVWA AEYSHWMNIK TILDELIQRG HEVTVLASSA SILFDPNNSS ALKIEIYPTS LTKTELENFI MQQIKRWSDL PKDTFWLYFS QVQEIMSIFG DITRKFCKDV VSNKKFMKKV QESRFDVIFA DAIFPCSELL AELFNIPFVY SLSFSPGYTF EKHSGGFIFP PSYVPVVMSE LTDQMTFMER VKNMIYVLYF DFWFEIFDMK KWDQFYSEVL GRPTTLSETM GKADVWLIRN SWNFQFPYPL LPNVDFVGGL HCKPAKPLPK EMEDFVQSSG ENGVVVFSLG SMVSNMTEER ANVIASALAQ IPQKVLWRFD GNKPDTLGLN TRLYKWIPQN DLLGHPKTRA FITHGGANGI YEAIYHGIPM VGIPLFADQP DNIAHMKARG AAVRVDFNTM SSTDLLNALK RVINDPSYKE NVMKLSRIQH DQPVKPLDRA VFWIEFVMRH KGAKHLRVAA HDLTWFQYHS LDVIGFLLVC VATVIFIVTK CCLFCFWKFA RKAKKGKND
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