Zinc finger protein 708 (ZNF708)

About Zinc finger protein 708

Zinc finger protein 708 (ZNF708) is a protein from Homo sapiens identified by UniProt accession P17019, 563 residues long. MolForge cross-references it against 0 known binders and 38 disease associations.

Target properties

Protein name	Zinc finger protein 708
UniProt accession	P17019
Gene	ZNF708
Organism	Homo sapiens
Length	563 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (38)

Diseases linked to this target (Open Targets).

hypertension · score 0.08
retinitis pigmentosa · score 0.07
pain · score 0.06
Leber congenital amaurosis · score 0.05
aniridia · score 0.05
Aniridia-intellectual disability syndrome · score 0.04
Familial ocular anterior segment mesenchymal dysgenesis · score 0.04
congenital glaucoma · score 0.04
retinitis pigmentosa 71 · score 0.04
isolated optic nerve hypoplasia · score 0.04

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-P17019-F1	alphafold	PREDICTED	76.20	—

Amino-acid sequence (563 residues)

MGPLTFMDVA IEFSLEEWQC LDTAQQNLYR NVMLENYRNL VFLGIAVSNL DLITCLEQGK EPWNMKRHEM AAKPPAMCSH FAKDLRPEQY IKNSFQQVIL RRYGKCGYQK GCKSVDEHKL HKGGHKGLNR CVTTTQSKIV QCDKYVKVFH KYSNAKRHKI RHTGKNPFKC KECGKSFCML SQLTQHEIIH TGEKPYKCEE CGKAFKKSSN LTNHKIIHTG EKPYKCEECG KAFNQSSTLT RHKIIHTGEK LYKCEECGKA FNRSSNLTKH KIVHTGEKPY KCEECGKAFK QSSNLTNHKK IHTGEKPYKC GECGKAFTLS SHLTTHKRIH TGEKPYKCEE CGKAFSVFST LTKHKIIHTE EKPYKCEECG KAFNRSSHLT NHKVIHTGEK PYKCEECGKA FTKSSTLTYH KVIHTGKKPY KCEECGKAFS IFSILTKHKV IHTEDKPYKC EECGKTFNYS SNFTNHKKIH TGEKPYKCEE CGKSFILSSH LTTHKIIHTG EKPYKCKECG KAFNQSSTLM KHKIIHTGEK PYKCEECGKA FNQSPNLTKH KRIHTKEKPY KCK

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards