About Rho-related GTP-binding protein RhoQ
Rho-related GTP-binding protein RhoQ (RHOQ) is a protein
from Homo sapiens identified by UniProt accession
P17081, 205 residues long.
MolForge cross-references it against 0 known binders and
47 disease associations.
Target properties
| Protein name | Rho-related GTP-binding protein RhoQ |
|---|
| UniProt accession | P17081 |
|---|
| Gene | RHOQ |
|---|
| Organism | Homo sapiens |
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| Length | 205 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (47)
Diseases linked to this target (Open Targets).
- cutaneous melanoma · score 0.14
- serum alanine aminotransferase measurement · score 0.11
- brain measurement · score 0.11
- neuroimaging measurement · score 0.11
- sitting height measurement · score 0.11
- head and neck squamous cell carcinoma · score 0.09
- lung adenocarcinoma · score 0.07
- arthritis · score 0.07
- Abnormality of refraction · score 0.07
- lymphocyte count · score 0.04
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-P17081-F1 | alphafold | PREDICTED | 89.15 | — |
Amino-acid sequence (205 residues)
MAHGPGALML KCVVVGDGAV GKTCLLMSYA NDAFPEEYVP TVFDHYAVSV TVGGKQYLLG LYDTAGQEDY DRLRPLSYPM TDVFLICFSV VNPASFQNVK EEWVPELKEY APNVPFLLIG TQIDLRDDPK TLARLNDMKE KPICVEQGQK LAKEIGACCY VECSALTQKG LKTVFDEAII AILTPKKHTV KKRIGSRCIN CCLIT
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