About Zinc finger protein 7
Zinc finger protein 7 (ZNF7) is a protein
from Homo sapiens identified by UniProt accession
P17097, 686 residues long.
MolForge cross-references it against 0 known binders and
44 disease associations.
Target properties
| Protein name | Zinc finger protein 7 |
|---|
| UniProt accession | P17097 |
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| Gene | ZNF7 |
|---|
| Organism | Homo sapiens |
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| Length | 686 residues |
|---|
| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
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| Max clinical phase | — |
|---|
Disease associations (44)
Diseases linked to this target (Open Targets).
- Blackfan-Diamond anemia · score 0.08
- hereditary persistence of fetal hemoglobin-sickle cell disease syndrome · score 0.08
- alpha thalassemia-intellectual disability syndrome type 1 · score 0.07
- Alpha-thalassemia - intellectual disability syndrome linked to chromosome 16 · score 0.07
- delta-beta-thalassemia · score 0.06
- hemoglobin D disease · score 0.06
- hemoglobin E-beta-thalassemia syndrome · score 0.06
- Alpha-thalassemia · score 0.05
- Beta-thalassemia · score 0.05
- hemolytic anemia due to adenylate kinase deficiency · score 0.05
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-P17097-F1 | alphafold | PREDICTED | 67.49 | — |
Amino-acid sequence (686 residues)
MEVVTFGDVA VHFSREEWQC LDPGQRALYR EVMLENHSSV AGLAGFLVFK PELISRLEQG EEPWVLDLQG AEGTEAPRTS KTDSTIRTEN EQACEDMDIL KSESYGTVVR ISPQDFPQNP GFGDVSDSEV WLDSHLGSPG LKVTGFTFQN NCLNEETVVP KTFTKDAPQG CKELGSSGLD CQPLESQGES AEGMSQRCEE CGKGIRATSD IALHWEINTQ KISRCQECQK KLSDCLQGKH TNNCHGEKPY ECAECGKVFR LCSQLNQHQR IHTGEKPFKC TECGKAFRLS SKLIQHQRIH TGEKPYRCEE CGKAFGQSSS LIHHQRIHTG ERPYGCRECG KAFSQQSQLV RHQRTHTGER PYPCKECGKA FSQSSTLAQH QRMHTGEKAQ ILKASDSPSL VAHQRIHAVE KPFKCDECGK AFRWISRLSQ HQLIHTGEKP YKCNKCTKAF GCSSRLIRHQ RTHTGEKPFK CDECGKGFVQ GSHLIQHQRI HTGEKPYVCN DCGKAFSQSS SLIYHQRIHK GEKPYECLQC GKAFSMSTQL TIHQRVHTGE RPYKCNECGK AFSQNSTLFQ HQIIHAGVKP YECSECGKAF SRSSYLIEHQ RIHTRAQWFY EYGNALEGST FVSRKKVNTI KKLHQCEDCE KIFRWRSHLI IHQRIHTGEK PYKCNDCGKA FNRSSRLTQH QKIHMG
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