About Homeobox protein Hox-B9
Homeobox protein Hox-B9 (HOXB9) is a protein
from Homo sapiens identified by UniProt accession
P17482, 250 residues long.
MolForge cross-references it against 0 known binders and
167 disease associations.
Target properties
| Protein name | Homeobox protein Hox-B9 |
|---|
| UniProt accession | P17482 |
|---|
| Gene | HOXB9 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 250 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (167)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.54
- Alzheimer disease · score 0.28
- multiple sclerosis · score 0.28
- lysosomal storage disease · score 0.28
- Parkinson disease · score 0.28
- low density lipoprotein cholesterol measurement · score 0.14
- neoplasm · score 0.11
- head and neck squamous cell carcinoma · score 0.09
- cancer · score 0.09
- non-small cell lung carcinoma · score 0.09
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-P17482-F1 | alphafold | PREDICTED | 63.54 | — |
Amino-acid sequence (250 residues)
MSISGTLSSY YVDSIISHES EDAPPAKFPS GQYASSRQPG HAEHLEFPSC SFQPKAPVFG ASWAPLSPHA SGSLPSVYHP YIQPQGVPPA ESRYLRTWLE PAPRGEAAPG QGQAAVKAEP LLGAPGELLK QGTPEYSLET SAGREAVLSN QRPGYGDNKI CEGSEDKERP DQTNPSANWL HARSSRKKRC PYTKYQTLEL EKEFLFNMYL TRDRRHEVAR LLNLSERQVK IWFQNRRMKM KKMNKEQGKE
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