Transcription factor JunD (JUND)

About Transcription factor JunD

Transcription factor JunD (JUND) is a protein from Homo sapiens identified by UniProt accession P17535, 347 residues long. MolForge cross-references it against 0 known binders and 318 disease associations.

Target properties

Protein name	Transcription factor JunD
UniProt accession	P17535
Gene	JUND
Organism	Homo sapiens
Length	347 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (318)

Diseases linked to this target (Open Targets).

neurodegenerative disease · score 0.37
eosinophil count · score 0.31
monocyte count · score 0.31
eosinophil percentage of leukocytes · score 0.24
triglyceride measurement · score 0.24
monocyte percentage of leukocytes · score 0.21
grip strength measurement · score 0.20
BMI-adjusted waist-hip ratio · score 0.18
BMI-adjusted waist circumference · score 0.17
waist-hip ratio · score 0.17

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-P17535-F1	alphafold	PREDICTED	62.19	—

Amino-acid sequence (347 residues)

METPFYGDEA LSGLGGGASG SGGSFASPGR LFPGAPPTAA AGSMMKKDAL TLSLSEQVAA ALKPAAAPPP TPLRADGAPS AAPPDGLLAS PDLGLLKLAS PELERLIIQS NGLVTTTPTS SQFLYPKVAA SEEQEFAEGF VKALEDLHKQ NQLGAGAAAA AAAAAAGGPS GTATGSAPPG ELAPAAAAPE APVYANLSSY AGGAGGAGGA ATVAFAAEPV PFPPPPPPGA LGPPRLAALK DEPQTVPDVP SFGESPPLSP IDMDTQERIK AERKRLRNRI AASKCRKRKL ERISRLEEKV KTLKSQNTEL ASTASLLREQ VAQLKQKVLS HVNSGCQLLP QHQVPAY

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards