Large ribosomal subunit protein eL33 (RPL35A)

About Large ribosomal subunit protein eL33

Large ribosomal subunit protein eL33 (RPL35A) is a protein from Homo sapiens identified by UniProt accession P18077, 110 residues long. MolForge cross-references it against 0 known binders and 54 disease associations.

Target properties

Protein name	Large ribosomal subunit protein eL33
UniProt accession	P18077
Gene	RPL35A
Organism	Homo sapiens
Length	110 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (54)

Diseases linked to this target (Open Targets).

Blackfan-Diamond anemia · score 0.75
Diamond-Blackfan anemia · score 0.72
Duchenne muscular dystrophy · score 0.50
cystic fibrosis · score 0.50
influenza · score 0.46
neurodegenerative disease · score 0.46
Abnormal radial ray morphology · score 0.37
Becker muscular dystrophy · score 0.29
qualitative or quantitative defects of dystrophin · score 0.26
aniridia · score 0.09

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-P18077-F1	alphafold	PREDICTED	95.59	—

Amino-acid sequence (110 residues)

MSGRLWSKAI FAGYKRGLRN QREHTALLKI EGVYARDETE FYLGKRCAYV YKAKNNTVTP GGKPNKTRVI WGKVTRAHGN SGMVRAKFRS NLPAKAIGHR IRVMLYPSRI

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards