Large ribosomal subunit protein uL30 (RPL7)

Homo sapiens — UniProt P18124

Gene: RPL7Homo sapiensSwissProt reviewed

About Large ribosomal subunit protein uL30

Large ribosomal subunit protein uL30 (RPL7) is a protein from Homo sapiens identified by UniProt accession P18124, 248 residues long. MolForge cross-references it against 0 known binders and 66 disease associations.

Target properties

Protein nameLarge ribosomal subunit protein uL30
UniProt accessionP18124
GeneRPL7
OrganismHomo sapiens
Length248 residues
Molecular weight—
EC numbers—
Target classUNCLASSIFIED
Subcellular location—
Keywords—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tierMEDIUM
Druggability score—
Pocket score—
Max clinical phase—

Disease associations (66)

Diseases linked to this target (Open Targets).

  • Duchenne muscular dystrophy · score 0.50
  • cystic fibrosis · score 0.50
  • influenza · score 0.46
  • Becker muscular dystrophy · score 0.29
  • clear cell renal carcinoma · score 0.27
  • qualitative or quantitative defects of dystrophin · score 0.26
  • appendicular lean mass · score 0.17
  • Varicose veins · score 0.13
  • brain measurement · score 0.13
  • Abnormality of refraction · score 0.13

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

StructureSourceMethodMean pLDDTResolution (Å)
AF-P18124-F1alphafoldPREDICTED93.92—

Amino-acid sequence (248 residues)

MEGVEEKKKE VPAVPETLKK KRRNFAELKI KRLRKKFAQK MLRKARRKLI YEKAKHYHKE YRQMYRTEIR MARMARKAGN FYVPAEPKLA FVIRIRGING VSPKVRKVLQ LLRLRQIFNG TFVKLNKASI NMLRIVEPYI AWGYPNLKSV NELIYKRGYG KINKKRIALT DNALIARSLG KYGIICMEDL IHEIYTVGKR FKEANNFLWP FKLSSPRGGM KKKTTHFVEG GDAGNREDQI NRLIRRMN

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Quick facts

UniProtP18124
GeneRPL7
OrganismHomo sapiens
Length248
Binders0
Diseases66
View on UniProt