About Vascular cell adhesion protein 1
Vascular cell adhesion protein 1 (VCAM1) is a protein
from Homo sapiens identified by UniProt accession
P19320, 739 residues long.
MolForge cross-references it against 0 known binders and
970 disease associations.
Target properties
| Protein name | Vascular cell adhesion protein 1 |
|---|
| UniProt accession | P19320 |
|---|
| Gene | VCAM1 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 739 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (970)
Diseases linked to this target (Open Targets).
- lymphocyte count · score 0.47
- monocyte count · score 0.42
- leukocyte count · score 0.42
- eosinophil count · score 0.39
- neurodegenerative disease · score 0.37
- secondary Parkinson disease · score 0.33
- myeloid white cell count · score 0.33
- open-angle glaucoma · score 0.29
- platelet-to-lymphocyte ratio · score 0.28
- eosinophil percentage of leukocytes · score 0.27
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-P19320-F1 | alphafold | PREDICTED | 84.28 | — |
Amino-acid sequence (739 residues)
MPGKMVVILG ASNILWIMFA ASQAFKIETT PESRYLAQIG DSVSLTCSTT GCESPFFSWR TQIDSPLNGK VTNEGTTSTL TMNPVSFGNE HSYLCTATCE SRKLEKGIQV EIYSFPKDPE IHLSGPLEAG KPITVKCSVA DVYPFDRLEI DLLKGDHLMK SQEFLEDADR KSLETKSLEV TFTPVIEDIG KVLVCRAKLH IDEMDSVPTV RQAVKELQVY ISPKNTVISV NPSTKLQEGG SVTMTCSSEG LPAPEIFWSK KLDNGNLQHL SGNATLTLIA MRMEDSGIYV CEGVNLIGKN RKEVELIVQE KPFTVEISPG PRIAAQIGDS VMLTCSVMGC ESPSFSWRTQ IDSPLSGKVR SEGTNSTLTL SPVSFENEHS YLCTVTCGHK KLEKGIQVEL YSFPRDPEIE MSGGLVNGSS VTVSCKVPSV YPLDRLEIEL LKGETILENI EFLEDTDMKS LENKSLEMTF IPTIEDTGKA LVCQAKLHID DMEFEPKQRQ STQTLYVNVA PRDTTVLVSP SSILEEGSSV NMTCLSQGFP APKILWSRQL PNGELQPLSE NATLTLISTK MEDSGVYLCE GINQAGRSRK EVELIIQVTP KDIKLTAFPS ESVKEGDTVI ISCTCGNVPE TWIILKKKAE TGDTVLKSID GAYTIRKAQL KDAGVYECES KNKVGSQLRS LTLDVQGREN NKDYFSPELL VLYFASSLII PAIGMIIYFA RKANMKGSYS LVEAQKSKV
Explore Vascular cell adhesion protein 1 with MolForge
Find binders, run structure-based screening, and map this target across
diseases and approved drugs with our AI-powered platform.
Browse all targets