About Alpha-1-acid glycoprotein 2
Alpha-1-acid glycoprotein 2 (ORM2) is a protein
from Homo sapiens identified by UniProt accession
P19652, 201 residues long.
MolForge cross-references it against 0 known binders and
232 disease associations.
Target properties
| Protein name | Alpha-1-acid glycoprotein 2 |
|---|
| UniProt accession | P19652 |
|---|
| Gene | ORM2 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 201 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (232)
Diseases linked to this target (Open Targets).
- breast adenocarcinoma · score 0.25
- blood protein measurement · score 0.19
- coagulation factor measurement · score 0.16
- testosterone measurement · score 0.13
- serum alanine aminotransferase measurement · score 0.12
- high density lipoprotein cholesterol measurement · score 0.11
- non-alcoholic fatty liver disease · score 0.10
- thrombin generation potential measurement · score 0.10
- hepatocellular carcinoma · score 0.09
- neoplasm · score 0.09
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-P19652-F1 | alphafold | PREDICTED | 91.20 | — |
Amino-acid sequence (201 residues)
MALSWVLTVL SLLPLLEAQI PLCANLVPVP ITNATLDRIT GKWFYIASAF RNEEYNKSVQ EIQATFFYFT PNKTEDTIFL REYQTRQNQC FYNSSYLNVQ RENGTVSRYE GGREHVAHLL FLRDTKTLMF GSYLDDEKNW GLSFYADKPE TTKEQLGEFY EALDCLCIPR SDVMYTDWKK DKCEPLEKQH EKERKQEEGE S
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