C-X-C motif chemokine 3 (CXCL3)

About C-X-C motif chemokine 3

C-X-C motif chemokine 3 (CXCL3) is a protein from Homo sapiens identified by UniProt accession P19876, 107 residues long. MolForge cross-references it against 0 known binders and 277 disease associations.

Target properties

Protein name	C-X-C motif chemokine 3
UniProt accession	P19876
Gene	CXCL3
Organism	Homo sapiens
Length	107 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (277)

Diseases linked to this target (Open Targets).

neurodegenerative disease · score 0.26
head and neck squamous cell carcinoma · score 0.18
monocyte count · score 0.16
neoplasm · score 0.10
attention deficit hyperactivity disorder · score 0.09
hepatocellular carcinoma · score 0.08
breast carcinoma · score 0.08
non-small cell lung carcinoma · score 0.08
calf circumference measurement · score 0.08
schizophrenia 15 · score 0.07

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-P19876-F1	alphafold	PREDICTED	81.87	—

Amino-acid sequence (107 residues)

MAHATLSAAP SNPRLLRVAL LLLLLVAASR RAAGASVVTE LRCQCLQTLQ GIHLKNIQSV NVRSPGPHCA QTEVIATLKN GKKACLNPAS PMVQKIIEKI LNKGSTN

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards