Elafin (PI3)

About Elafin

Elafin (PI3) is a protein from Homo sapiens identified by UniProt accession P19957, 117 residues long. MolForge cross-references it against 0 known binders and 288 disease associations.

Target properties

Protein name	Elafin
UniProt accession	P19957
Gene	PI3
Organism	Homo sapiens
Length	117 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (288)

Diseases linked to this target (Open Targets).

breast adenocarcinoma · score 0.24
head and neck squamous cell carcinoma · score 0.22
blood protein measurement · score 0.19
esophageal cancer · score 0.17
squamous cell lung carcinoma · score 0.17
gastric adenocarcinoma · score 0.16
eye colour measurement · score 0.11
low grade glioma · score 0.11
psoriasis · score 0.10
neoplasm · score 0.10

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-P19957-F1	alphafold	PREDICTED	72.22	—

Amino-acid sequence (117 residues)

MRASSFLIVV VFLIAGTLVL EAAVTGVPVK GQDTVKGRVP FNGQDPVKGQ VSVKGQDKVK AQEPVKGPVS TKPGSCPIIL IRCAMLNPPN RCLKDTDCPG IKKCCEGSCG MACFVPQ

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards