About Annexin A7
Annexin A7 (ANXA7) is a protein
from Homo sapiens identified by UniProt accession
P20073, 488 residues long.
MolForge cross-references it against 0 known binders and
222 disease associations.
Target properties
| Protein name | Annexin A7 |
|---|
| UniProt accession | P20073 |
|---|
| Gene | ANXA7 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 488 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (222)
Diseases linked to this target (Open Targets).
- neoplasm · score 0.10
- gastric adenocarcinoma · score 0.08
- hepatocellular carcinoma · score 0.07
- lung adenocarcinoma · score 0.07
- cancer · score 0.07
- Hyperlipoproteinemia type 1 · score 0.07
- Familial cerebral saccular aneurysm · score 0.06
- essential thrombocythemia · score 0.06
- chronic pancreatitis · score 0.06
- beta-thalassemia-X-linked thrombocytopenia syndrome · score 0.06
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-P20073-F1 | alphafold | PREDICTED | 76.12 | — |
Amino-acid sequence (488 residues)
MSYPGYPPTG YPPFPGYPPA GQESSFPPSG QYPYPSGFPP MGGGAYPQVP SSGYPGAGGY PAPGGYPAPG GYPGAPQPGG APSYPGVPPG QGFGVPPGGA GFSGYPQPPS QSYGGGPAQV PLPGGFPGGQ MPSQYPGGQP TYPSQINTDS FSSYPVFSPV SLDYSSEPAT VTQVTQGTIR PAANFDAIRD AEILRKAMKG FGTDEQAIVD VVANRSNDQR QKIKAAFKTS YGKDLIKDLK SELSGNMEEL ILALFMPPTY YDAWSLRKAM QGAGTQERVL IEILCTRTNQ EIREIVRCYQ SEFGRDLEKD IRSDTSGHFE RLLVSMCQGN RDENQSINHQ MAQEDAQRLY QAGEGRLGTD ESCFNMILAT RSFPQLRATM EAYSRMANRD LLSSVSREFS GYVESGLKTI LQCALNRPAF FAERLYYAMK GAGTDDSTLV RIVVTRSEID LVQIKQMFAQ MYQKTLGTMI AGDTSGDYRR LLLAIVGQ
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